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Fig. 6 | BMC Systems Biology

Fig. 6

From: Prior knowledge guided active modules identification: an integrated multi-objective approach

Fig. 6

Visualization of module 3 identified by the proposed algorithm in network 2. Each node represents for a gene. The setting for node color is the same with Fig. 2. The turning point between red and green is set to the value τ=7.71×10−6. Three rectangle shaped nodes with black border are genes involved in drug export and are highly consistent in all modules. YDR406W is an ATP-binding cassette multidrug transporter. YDR011W is a ATP-binding cassette transporter. YOR153W is also an ATP-binding cassette multidrug transporter. The three genes serve as an important role in yeast’s resistance to diclofenac

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