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Table 2 Gene ontology results of modules detected by jActiveModule in network 1

From: Prior knowledge guided active modules identification: an integrated multi-objective approach

Module Size S A R A Typical GO terms p-value
1 26 250.39 1 galactose catabolic process via UDP-galactose 3.42×10−04
     glycolytic fermentation to ethanol 2.72×10−03
     amino acid catabolic process to alcohol via Ehrlich pathway 1.25×10−02
2 5 58.21 0 response to heat 2.16×10−03
3 16 270.79 2 galactose catabolic process via UDP-galactose 4.85×10−05
4 18 169.89 2 galactose catabolic process via UDP-galactose 1.15×10−04
     cellular carbohydrate metabolic process 3.27×10−02
5 4 37.05 0 None Not available
  1. S A and R A are the objective functions of active module score and KEGG pathway coverage score, respectively. The values are calculated by the proposed objective functions using the same parameters setting as the proposed algorithm. τ=1.76×10−4 and R ratio =0.6
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BMC Systems Biology

ISSN: 1752-0509

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