Table 4 Gene ontology results of 3 modules on Pareto front detected by the proposed algorithm in network 2
From: Prior knowledge guided active modules identification: an integrated multi-objective approach
| Module | Size | S A | R A | Typical GO terms | p-value |
|---|---|---|---|---|---|
| 1 | 34 | 91.01 | 0 | Drug export | 1.79×10−03 |
| Cellular response to drug | 4.71×10−02 | ||||
| 2 | 39 | 57.56 | 4 | Drug export | 2.84×10−03 |
| 3 | 62 | 46.332 | 8 | Drug export | 1.21×10−02 |
| Amino acid catabolic process to alcohol via Ehrlich pathway | 8.65×10−09 | ||||
| Ethanol metabolic process | 3.71×10−06 | ||||
| NADH oxidation | 3.73×10−03 | ||||
| Glycolytic process | 4.34×10−03 | ||||
| Fermentation | 1.40×10−02 | ||||
| Macromolecule metabolic process | 2.51×10−02 |