Table 4 Gene ontology results of 3 modules on Pareto front detected by the proposed algorithm in network 2
From: Prior knowledge guided active modules identification: an integrated multi-objective approach
Module | Size | S A | R A | Typical GO terms | p-value |
|---|---|---|---|---|---|
1 | 34 | 91.01 | 0 | Drug export | 1.79×10−03 |
|  |  |  |  | Cellular response to drug | 4.71×10−02 |
2 | 39 | 57.56 | 4 | Drug export | 2.84×10−03 |
3 | 62 | 46.332 | 8 | Drug export | 1.21×10−02 |
|  |  |  |  | Amino acid catabolic process to alcohol via Ehrlich pathway | 8.65×10−09 |
|  |  |  |  | Ethanol metabolic process | 3.71×10−06 |
|  |  |  |  | NADH oxidation | 3.73×10−03 |
|  |  |  |  | Glycolytic process | 4.34×10−03 |
|  |  |  |  | Fermentation | 1.40×10−02 |
|  |  |  |  | Macromolecule metabolic process | 2.51×10−02 |