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Fig. 2 | BMC Systems Biology

Fig. 2

From: Making life difficult for Clostridium difficile: augmenting the pathogen’s metabolic model with transcriptomic and codon usage data for better therapeutic target characterization

Fig. 2

Genetic analysis using multi-objective optimization. Regions of objective space explored by the optimization algorithm for the objectives of maximization of biomass and minimization of total intracellular flux. Solutions are represented by progressively warmer colors depending on the time step of the algorithm in which they had been adaptively generated from the initial point. The Pareto front is shown in black in the inset

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