Skip to main content

Table 6 Controllability and observability index values for the model of ERK activation controlled via the EGFR pathway

From: A combined model reduction algorithm for controlled biochemical systems

Lumped Controllability Observability Input-output
state-variable index index index
x 1(t) 0.3022 0.0176 0.0053
x 2(t) 0.0201 0.0153 0.0003
x 3(t) 0.0189 0.0009 1.681×10−5
x 4(t) 0.8547 0.2752 0.2352
x 5(t) 0.6194 0.0079 0.0049
x 6(t) 1 1 1
x 7(t) 0.1412 0.1043 0.0147
x 8(t) 0.1378 0.0018 0.0003
x 9(t) 0.1539 0.0164 0.0025
x 10(t) 0.0473 0.0092 0.0004
x 11(t) 0.3312 0.0442 0.0146