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Table 1 Reaction rates considered in the model

From: A new efficient approach to fit stochastic models on the basis of high-throughput experimental data using a model of IRF7 gene expression as case study

Name Definition
f IFN \(V_{IFN}\left (\frac {IFN^{n}}{k^{n}_{IFN}+IFN^{n}}\right)\)
f dIFN k dIFN ·I F N
f I S G F3 k I S G F3·I F N
f d I S G F3 k d I S G F3·I S G F3
\(f_{P_{a}}\) \(k_{on}\left (\frac {ISGF3 \cdot IRF7dimer}{k_{aI3} \cdot k_{aI7} + k_{aI3} \cdot ISGF3 + k_{aI7}\cdot IRF7dimer + ISGF3 \cdot IRF7dimer}\right)(1-P_{a})\)
\(f_{dP_{a}}\) k off ·P a
\(f_{mRNA_{A}}\) k Active ·P a
\(f_{mRNA_{B}}\) k Basal (1−P a )
f dmRNA k dmRNA ·m R N A
f I R F7 k I R F7·m R N A
f I R F7p h o s p k d I R F7·I R F7
f I R F7d i m e r k I R F7d i m e r ·I R F7p h o s p·I R F7p h o s p
f d I R F7d i m e r k d I R F7d i m e r ·I R F7d i m e r