Fig. 8
From: Dynamic genome-scale metabolic modeling of the yeast Pichia pastoris
Final HSA vs. final biomass concentrations of simulated batch cultivations of single knock-out-strains. Blue dots correspond to the output of strains that improved the initial final HSA concentration (30Â mg/L). Candidates out of Cluster II were manually analyzed. The red circle indicates the performance of the parental strain and the black arrow points to the methylene tetrahydrofolate dehydrogenase knock-out strain