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Table 9 Feeding policies evaluated to improve the production of Serum Albumin in a particular bioreactor setup

From: Dynamic genome-scale metabolic modeling of the yeast Pichia pastoris

Strategy μMAX Rate μMIN qP [mg/g · h] XFINAL [g/L] PFINAL [mg/L] Limitation
1 0.14 - - 2.85 164.8 138 Oxygen
2 0.12 - - 2.59 187.8 135 Oxygen
3 0.1 - - 2.32 195.3 130 Volume
4 0.08 - - 2.29 191.3 138 Volume
5 0.06 - - 2.28 184.7 154 Volume
Best 0.14 0.1 0.08 2.83 197.5 150 Volume
  1. This table shows the process indicators for the constant feeding Strategies (1–5) plus the best decreasing growth rate strategy. μMAX is the maximum growth rate in the feeding police. μMIN is the minimum growth rate in the feeding police. Rate is the rate of decreasing of set growth rate in feeding police. qP is the protein productivity. XFINAL and PFINAL refer to the final concentration of biomass and serum albumin in the reactor when the simulation stops, which happened by either violating user-defined volume or Oxygen Transfer thresholds