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Table 3 Most prominent dysregulated miRNAs commonly associated to the partial UUO model and human UPJ obstruction

From: Systems biology combining human- and animal-data miRNA and mRNA data identifies new targets in ureteropelvic junction obstruction

miRNA

UPJ vs Healthy (urine)

Partial UUO vs Sham (kidney)

FC

p-value

FC

p-value

let-7a-5p

−1,559

0,003

−3,558

0,004

miR-16-5p

−1,293

0,002

−2,913

0,0007

miR-29b-3p

−1,153

0,03

10,073

3,10E-08

miR-125b-5p

−1,18

0,03

−3,219

0,003

miR-26a-5p

−1,376

0,03

−3,175

0,001

  1. FC fold change
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BMC Systems Biology

ISSN: 1752-0509

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