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Table 5 Most prominent deregulated mRNA targets in obstructive nephropathy

From: Systems biology combining human- and animal-data miRNA and mRNA data identifies new targets in ureteropelvic junction obstruction

Gene symbol

Description

FC

p-value

let-7a-5p

miR-125b-5p

miR-16-5p

miR-26a-5p

miR- 29b-3p

Dtx4

 E3 ubiquitin-protein ligase or deltex 4 homolog (Drosophila)

2,41

0,001

√

√

   

Lmod1

 Leiomodin 1 (smooth muscle)

1,57

0,001

 

√

√

  

Adamts19

 A disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 19

2,97

0,0006

   

√

√

Nav1

 Neuron navigator 1

1,57

0,002

   

√

√

  1. FC fold change