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Table 1 Time complexity comparison

From: Detection of statistically significant network changes in complex biological networks

dGHD

Closed-form

O(N 2|E|)

O(N|E|+N log(N)+K 2|E|)

  1. Here K represents the number of nodes for which p-value is greater than θ and generally KN. An important remark is that the cGHD calculation after removal of each node can be done independently in parallel. So, in case we have T processors, the complexity of the proposed approach will reduce ≈ linearly w.r.t. T