Fig. 5

Profile on change of perturbation scores of the member genes in the identified common network (HDF senescence dataset). a Change of perturbation scores during senescence process. There were two striking patterns, one of which is gradually decreased pattern and the other is gradually increased pattern. b Comparison for changes of perturbation scores in adjacent two time points and the first and the last time point. We could identify that the changing pattern was reversed at both the first and the last time point. As a statistical result shown in Table 2, this reversely changed pattern of expression is rarely happen. Therefore, we could assume that the common network included information to explain the senescence process