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Table 5 On the common network from HDF senescence dataset, the list of top 10 terms of functional enrichment test with KEGG pathway and Gene Ontology database. (P-value < 0.01)

From: Systematic identification of an integrative network module during senescence from time-series gene expression

Category

Term

-Log10 (P-value)

KEGG pathway

Cell cycle

8.292

Pathways in cancer

7.553

Small cell lung cancer

6.699

p53 signaling pathway

6.301

Focal adhesion

6.000

Prostate cancer

5.398

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

3.824

Melanoma

3.032

Hypertrophic cardiomyopathy (HCM)

2.678

Dilated cardiomyopathy

2.523

Gene Ontology

(Biological Process)

response to endogenous stimulus

11.780

regulation of cell proliferation

11.513

negative regulation of cell proliferation

11.209

response to hormone stimulus

10.919

organ development

10.213

response to organic cyclic substance

10.052

negative regulation of epithelial cell proliferation

9.901

response to steroid hormone stimulus

9.870

response to organic substance

9.744

system development

9.547