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Fig. 5 | BMC Systems Biology

Fig. 5

From: Delineating functional principles of the bow tie structure of a kinase-phosphatase network in the budding yeast

Fig. 5

mRNA and protein turnover related properties of KPs in the different layers of the KP-Net. Distribution of (a) mRNA synthesis rate, (b) mRNA half-life, (c) mRNA abundance, (d) mRNA translation rate, (e) protein half-life, (f) protein abundance, (g) percentage of noisy mRNA KPs and (h) distribution of noise in KP protein abundance of KPs in the different layers of the KP-Net. A KP is considered to be noisy at the transcriptomic level, if the promoter region of its gene was predicted to contain a TATA-box consensus sequence. Protein noise was defined as the distance of coefficient of variation (CV) of protein abundance from a running median of protein abundance CV. For description of box plots and bar plots, see Fig. 3 and for description of used datasets see Supplementary Materials in Additional file 1

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