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Fig. 5 | BMC Systems Biology

Fig. 5

From: Parameter inference for stochastic single-cell dynamics from lineage tree data

Fig. 5

The proposed tree-based inference method outperforms the traditionally used inference on independent cell trajectories. Posterior distributions of the six unknown parameters presented in Example 2, obtained both with tree-based (green) and trajectory-based inference (blue). The red bars are positioned at the true parameter values (i.e. the ones used for data generation), while the dashed lines indicate the estimated posterior means. The curves are obtained by smoothing of the normalized histograms of the MCMC samples. One can clearly observe the bias in the parameter estimates when trajectory-based inference was used

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