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Fig. 2 | BMC Systems Biology

Fig. 2

From: Parameter identifiability analysis and visualization in large-scale kinetic models of biosystems

Fig. 2

Circadian clock in Arabidopsis thaliana: panel a shows the model sensitivities with respect to parameters in logarithmic scale. In panel b the maximum number of identifiable parameters is depicted as a function of the collinearity threshold. The red vertical line indicates our choice of threshold (CI =20) used for further analysis. In panel c the interplay among the collinear parameters is indicated up to groups of 3 parameters. In panel d the mathematical model is depicted. Nodes indicate states (yellow), identifiable (green) and not identifiable (red) parameters, and observables (blue). Highly correlated parameter pairs are connected by undirected edges

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