Emergence of microbial diversity due to cross-feeding interactions in a spatial model of gut microbial metabolism

BMC Systems Biology

Table 1 Parameters of the spatially explicit model

Parameter	Value	Units	Comments
Δt	3.0	min
Δx	1.0	cm
Grid length	150	Grid sites
Grid height	10	Grid sites
TIME_END	4000	hr
# slots per grid point	2
DENS_MAX	1.0	g DW·l ⁻¹	See main text
Initial density	50%		Assumed
TIME_FOOD	8	hr	Assumed
FOOD_IN	42	mmol	Assumed
Diffusion constant	14000	μ m ²/s	Assumed (compare 900 μ m ²/s glucose in water)
P_MOVECELL	0.05		Assumed
DEATH_BASAL	0.025	h r ⁻¹	Assumed
DEATH_DENS	2.0	h r ⁻¹	Assumed
TIME_DRIFT	15	min	Passage time of approximately 40 hrs
P_CELL_FLOW	Variable
UPTAKE_HOST	Variable
μ_DEL	0.002		Assumed
μ_BIRTH	0.0002		Assumed
μ_POINT	0.002		Assumed
μ_POINT_STEP	0.2		Assumed

ISSN: 1752-0509