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Table 4 Comparison experimental and simulated yields of wild type and mutant strains of Clostridium butyricum W5 cultured in glucose [71]

From: Clostridium butyricum maximizes growth while minimizing enzyme usage and ATP production: metabolic flux distribution of a strain cultured in glycerol

Product

Experimental yields

Simulated yields (FVA range)

Wild strain

Mutant strain

Wild strain (FBA)

Mutant strain (ROOM)

H2

1.25a

0.69

0.661 (0.046–1.345)

0.694 (0–1.787)

Ethanol

0.18

3.31 a

0.215 (0–0.714)

0.680 (0–1.069)

Biomassb

100%

99.2%a

100%

95.0%

  1. aValues calculated from information reported by Cai et al. [71]
  2. bYields reported as percentages based on the wild type strain
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BMC Systems Biology

ISSN: 1752-0509

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