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Table 2 Differentially expressed genes following α2B-adrenoceptor activation compared with vehicle-treated control according to IPA

From: Gene expression profiles and signaling mechanisms in α2B-adrenoceptor-evoked proliferation of vascular smooth muscle cells

Gene symbol Gene name Fold change P-value
Up-regulated genes
 Lypd8 LY6/PLAUR domain containing 8 2.01 4.2·10−6
 Glrx glutaredoxin 1.60 1.0·10−3
 LOC500300 similar to hypothetical protein MGC6835 (Depp) 1.58 4.0·10−3
 Procr protein C receptor 1.56 5.7·10−3
 Egr1 early growth response 1 1.54 5.0·10−3
 Rpl37 ribosomal protein L37 1.51 1.0·10−3
 Kif20a kinesin family member 20a 1.47 1.3·10−2
 Oasl 2′-5′-oligoadenylate synthetase-like 1.46 5.0·10−3
 Fam25a family with sequence similarity 25, member A 1.45 4.0·10−3
 Ppial4g peptidylprolyl isomerase A like 4G 1.45 2.3·10−2
Down-regulated genes
 Cx3cl1 chemokine (C-X3-C motif) ligand 1 −1.86 1.7·10−5
 Ccl2 chemokine (C-C motif) ligand 2 −1.74 4.4·10−4
 Ahnak AHNAK nucleoprotein −1.47 2.3·10−2
 Npm3 nucleophosmin/nucleoplasmin 3 −1.45 3.0·10−2
 Nid1 nidogen 1 −1.44 8.7·10−3
 Tnnt2 troponin T2, cardiac type −1.42 6.0·10−3
 Zfp36l2 zinc finger protein 36, C3H type-like 2 −1.40 4.4·10−2
 Ccl7 chemokine (C-C motif) ligand 7 −1.40 2.0·10−2
 Cav1 caveolin 1 −1.39 8.2·10−3
 Rhoa ras homolog family member A −1.38 2.4·10−2