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Fig. 4 | BMC Systems Biology

Fig. 4

From: An agent-based model of triple-negative breast cancer: the interplay between chemokine receptor CCR5 expression, cancer stem cells, and hypoxia

Fig. 4

Simulated tumor growth of MB231 cells under different conditions. a We investigate three doses of a drug treatment targeting cancer stem cells starting at day 150 with varying efficacy at killing cancer stem cells between 50%–90%. Plot of the mean total cell numbers over time after multiple doses of treatment. b Plot of the mean stem cell numbers over time after multiple doses of a drug treatment targeting cancer stem cells. c A semi-log plot comparison of MB231 primary tumors under control, hypoxic, and maraviroc conditions. d A plot of MB231 primary tumor under control, hypoxic, and maraviroc conditions

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