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Fig. 1 | BMC Systems Biology

Fig. 1

From: Manatee invariants reveal functional pathways in signaling networks

Fig. 1

Petri net (PN) of a Michaelis-Menten reaction scheme. a The PN describes the synthesis and degradation of an enzyme E, which catalyzes the conversion of the substrate S to the product P. The network has two transition invariants (TI), T I 1 =(syn S, bin, rel, deg P) and T I 2=(syn E, deg E), and therefore is covered by transition invariants (CTI). It has no place invariant (PI). b The T I 1-induced network, which covers the process of the conversion of S to P, exhibits a PI, which describes the regaining of the enzyme E, either bound in the E:S complex or as the free enzyme E

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