Fig. 4

In silico knockout matrix of the PN in Fig. 3 based on Manatee invariants (MI). The rows of the matrix represent a certain protein knockout, while the columns represent the proteins or protein complexes that may be affected by the respective knockout. A red entry denotes a negative effect for the protein complex, whereas a green entry denotes no effect. The effects that were obtained only for MI-based analysis compared to the TI-based computation are labeled by an asterisk