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Table 1 Comparison of Snoopy’s hybrid simulator with two other similar tools

From: Snoopy’s hybrid simulator: a tool to construct and simulate hybrid biological models

Features Tools Snoopy’s hybrid simulator COPASI [16] VCell [17]
Use of graphical notations to specify model reactions Yes No Yes
Use of a parameterised language to manage larger models Yes No No
Support unstiff ODE solvers Yes Yes Yes
Support stiff ODE solvers Yes Yes Yes
Improving simulation performance by analysing the model structure Yes No No
Interplay of stochastic and deterministic modules Variable Fixed Fixed
Exact hybrid simulation Yes Yes No
Platform-independent Yes Yes Yes
Availability Free Free Free