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Table 1 Comparison of Snoopy’s hybrid simulator with two other similar tools

From: Snoopy’s hybrid simulator: a tool to construct and simulate hybrid biological models

Features Tools

Snoopy’s hybrid simulator

COPASI [16]

VCell [17]

Use of graphical notations to specify model reactions

Yes

No

Yes

Use of a parameterised language to manage larger models

Yes

No

No

Support unstiff ODE solvers

Yes

Yes

Yes

Support stiff ODE solvers

Yes

Yes

Yes

Improving simulation performance by analysing the model structure

Yes

No

No

Interplay of stochastic and deterministic modules

Variable

Fixed

Fixed

Exact hybrid simulation

Yes

Yes

No

Platform-independent

Yes

Yes

Yes

Availability

Free

Free

Free