Table 2 Performance measures of the three implemented algorithms in Snoopy’s hybrid simulator
From: Snoopy’s hybrid simulator: a tool to construct and simulate hybrid biological models
Measures ∖Models | Model Information | Runtimes of Simulation Algorithms (sec.) | ||||
|---|---|---|---|---|---|---|
Species (Discrete) | Reactions (Stochastic) | Stochastic Events | Haseltine& Rawlings ∗ | Accelerated Method | Improved HRSSA | |
T7 Phage (1,000 runs) | 3 (2) | 6 (4) | 4,238,978 | 120.2 | 41.7 (281%) | 26.6 (452%) |
ATM/p53/NF- κB | 62 (14) | 119 (24) | 3,726 | 6.3 | 1.9 (332%) | 0.96 (656%) |
Cell Cycle Model | 26 (14) | 51 (20) | 762,612 | 870.4 | 625.7 (139%) | 365.5 (238%) |
Calcium Model (Fig. 2) | 10,006 (6) | 49,607 (6) | 29 | 215.8 | 220.7 (-1.1%) | 190 (1.13%) |