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Table 2 Performance measures of the three implemented algorithms in Snoopy’s hybrid simulator

From: Snoopy’s hybrid simulator: a tool to construct and simulate hybrid biological models

Measures Models Model Information Runtimes of Simulation Algorithms (sec.)
  Species (Discrete) Reactions (Stochastic) Stochastic Events Haseltine& Rawlings Accelerated Method Improved HRSSA
T7 Phage (1,000 runs) 3 (2) 6 (4) 4,238,978 120.2 41.7 (281%) 26.6 (452%)
ATM/p53/NF- κB 62 (14) 119 (24) 3,726 6.3 1.9 (332%) 0.96 (656%)
Cell Cycle Model 26 (14) 51 (20) 762,612 870.4 625.7 (139%) 365.5 (238%)
Calcium Model (Fig. 2) 10,006 (6) 49,607 (6) 29 215.8 220.7 (-1.1%) 190 (1.13%)
  1. *This refers to the algorithm version which exactly accounts for Eq. (1)