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Table 2 The performance comparison on the Gavin data set in terms of normalized AUC values

From: A two-step framework for inferring direct protein-protein interaction network from AP-MS data

 

BGS

PCA

Y2H

 

Initial

Filtered(ND)

Filtered(Silencer)

Initial

Filtered(ND)

Filtered(Silencer)

Initial

Filtered(ND)

Filtered(Silencer)

SA

0.78

0.79 ↑

0.79 ↑

0.76

0.76 ↓

0.76 ↓

0.77

0.80 ↑

0.81 ↑

PE

0.63

0.77 ↑

0.73 ↑

0.62

0.74 ↑

0.71 ↑

0.54

0.76 ↑

0.68 ↑

DC

0.71

0.74 ↑

0.77 ↑

0.64

0.70 ↑

0.72 ↑

0.73

0.80 ↑

0.82 ↑

Hart

0.75

0.77 ↑

0.77 ↑

0.73

0.73 ↓

0.74 ↑

0.77

0.82 ↑

0.83 ↑

  1. In the table, the symbol ↑highlights the case that the normalized AUC value is increased in the curve derived from the filtered network. If there is no improvement, then ↓ is used instead