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Table 1 Standard parameter values in the model (5)−(8)

From: Glioma cell fate decisions mediated by Dll1-Jag1-Fringe in Notch1 signaling pathway

Parameters Definitions Values Unit
N 0 The innate production rates of Notch1 1400 Number of proteins
D 0 The innate production rates of Dll1 1600 Number of proteins
J 0 The innate production rates of Jag1 1200 Number of proteins
I 0 The innate production rates of NICD 200 Number of proteins
γ The degradation rate of proteins 0.1 time −1(h −1)
  Notch1, Jag1, and Dll1   
γ I The degradation rate of NICD 0.5 time −1(h −1)
k t The strengths of trans-activation 4.7×10−5 time −1(h −1)
k c The strengths of cis-activation 6.1×10−4 time −1(h −1)
  1. Values for Figs. 3 and 4