Table 3 Standard parameter values in the model (19)−(26)

N ₀

The innate production rates of Notch1

1600

Number of proteins

D ₀

The innate production rates of Dll1

1800

Number of proteins

J ₀

The innate production rates of Jag1

1200

Number of proteins

I ₀

The innate production rates of NICD

200

Number of proteins

γ

The degradation rate of proteins

0.1

time ⁻¹(h ⁻¹)

Notch1, Jag1, and Dll1

γ _I

The degradation rate of NICD

\(0.6^{\divideontimes },0.5^{*}\)

time ⁻¹(h ⁻¹)

k _t

The strengths of trans-activation

\( (7\times 10^{-6})^{\divideontimes },\)

time ⁻¹(h ⁻¹)

(10⁻⁵)^∗

k _c

The strengths of cis-activation

\( (4\times 10^{-4})^{\divideontimes },\)

time ⁻¹(h ⁻¹)

(6.1×10⁻⁴)^∗