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Table 3 Standard parameter values in the model (19)−(26)

From: Glioma cell fate decisions mediated by Dll1-Jag1-Fringe in Notch1 signaling pathway

Parameters Definitions Values Unit
N 0 The innate production rates of Notch1 1600 Number of proteins
D 0 The innate production rates of Dll1 1800 Number of proteins
J 0 The innate production rates of Jag1 1200 Number of proteins
I 0 The innate production rates of NICD 200 Number of proteins
γ The degradation rate of proteins 0.1 time −1(h −1)
  Notch1, Jag1, and Dll1   
γ I The degradation rate of NICD \(0.6^{\divideontimes },0.5^{*}\) time −1(h −1)
k t The strengths of trans-activation \( (7\times 10^{-6})^{\divideontimes },\) time −1(h −1)
   (10−5)  
k c The strengths of cis-activation \( (4\times 10^{-4})^{\divideontimes },\) time −1(h −1)
   (6.1×10−4)  
  1. \(\divideontimes \)Values for Fig. 6 a. *Values for Fig. 6 b