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Table 4 Standard parameter values in the model (27)−(34)

From: Glioma cell fate decisions mediated by Dll1-Jag1-Fringe in Notch1 signaling pathway

Parameters

Definitions

Values

Unit

N 0

The innate production rates of Notch1

1600

Number of proteins

D 0

The innate production rates of Dll1

1800

Number of proteins

J 0

The innate production rates of Jag1

1200

Number of proteins

I 0

The innate production rates of NICD

200

Number of proteins

γ

The degradation rate of proteins

0.1

time −1(h −1)

 

Notch1, Jag1, and Dll1

  

γ I

The degradation rate of NICD

0.5

time −1(h −1)

k t

The strengths of trans-activation

7×10−6

time −1(h −1)

k c

The strengths of cis-activation

6.1×10−4

time −1(h −1)

  1. Values for Fig. 7