Fig. 6

FoxM1 breast cancer regulon. GPU-ARACNE predicted FoxM1 breast cancer specific regulon, centered by FoxM1 as the transcription factor, connecting to its predicted transcriptional gene targets (other circles). FoxM1 targets were color coded according to the evidence validating their biological relevance. NCBI curated database reported targets were colored as pink ones; Literature reported by experiments were colored as orange ones. All edge length and thickness were weighted by the estimated Mutual information between targets and FoxM1. The closer one target is to FoxM1, the stronger the interaction is