Fig. 4

Mutation pattern of drug target genes belonging to cancer genes. The TargetCancer represented the common genes between anticancer drug targets and cancer genes. The TargetOnly represented the genes only belonging to genes encoding drug targets with mutation data. The CancerOnly represented the genes only belonging to cancer genes with mutation data. The Other represented genes with mutation data excluding the genes from above three gene sets. a Comparison of average mutation frequency of four gene sets. b Percentage of genes with at least 2% mutation frequency in the Pan-Cancer. c The function classification, mutation frequency in individual cancer type and Pan-Cancer, and numbers of drugs of 32 TargetCancer genes. We highlighted the mutation frequency higher than 5% of samples in “TargetCancer” genes with red color