From: Roles of alternative splicing in modulating transcriptional regulation
Up-regulated targets | Down-regulated targets | ||
---|---|---|---|
Molecular and Cellular Functions | |||
 Cell Death and Survival | 25 | Cell Morphology | 15 |
 Cell Morphology | 7 | Molecular Transport | 8 |
 Cellular Development | 8 | Protein Synthesis | 3 |
 Cellular Growth and Proliferation | 7 | Protein Trafficking | 2 |
 Post-Translational Modification | 16 | Cell-To-Cell Signaling and Interaction | 7 |
Diseases and Disorders | |||
 Infectious Disease | 6 | Developmental Disorder | 11 |
 Cancer | 101 | Hereditary Disorder | 21 |
 Organismal Injury and Abnormalities | 103 | Metabolic Disease | 13 |
 Tumor Morphology | 3 | Organismal Injury and Abnormalities | 65 |
 Connective Tissue Disorders | 10 | Renal and Urological Disease | 10 |