Fig. 1From: System modeling reveals the molecular mechanisms of HSC cell cycle alteration mediated by Maff and Egr3 under leukemiaDifferential expression profiles of Maff and Egr3 during leukemia progression. a According to microarray data, Maff and Egr3 are significantly highly expressed under leukemia. Their expressions reach the highest levels at the late stage (≥ Day 14) of leukemia, which are shown herein. The x- and y- axes are the log2 values of gene expression intensities in the microarray (leukemia and control, respectively); and the two red dashed lines (parallel to the diagonal) represent expression levels that are of 2-fold changes comparing to control, which serve as conventional indicators for significant changes in gene expression. b Relative expression levels of the two genes measured by qRT-PCR are shown. The data validate the high expressions of the two genes in HSCs under leukemiaBack to article page