Table 7 Parameter estimates that yield best fit and comparison with estimates in literature

Minimum number of ANP divisions

1

Maximum number of ANP divisions

4

-

Renewal probability of ANP

0.1

-

Expected number of ANP divisions

1.17

2

Expected ANP G ₁-phase duration

12hr

-

Minimum ANP G ₁-phase duration

3hr

-

Expected ANP S-phase duration

12hr

12hr

Minimum ANP S-phase duration

4hr

-

Expected ANP G ₂ M-phase duration

1hr

2hr

Minimum ANP G ₂ M-phase duration

0.5hr

-

Expected ANP-NB¹ duration

12hr

30hr

Minimum ANP-NB duration

3hr

-

Expected ANP-Apop² duration

48hr

-

Minimum ANP-Apop duration

2hr

-

Expected NB duration

260hr

60hr & 306hr³

Shape parameter of NB duration distribution

2

-

Minimum NB duration

20hr

-

Expected apoptotic cell duration

1.4hr

-

Cell death rate of ANP G ₁-phase

0.14

-

Cell death rate of ANP S-phase

0

-

Cell death rate of ANP G ₂ M-phase

0.02

-

Cell death rate of nonproliferating ANP

0.33

-

Cell death rate of NB

0.97

-

Minimum number of NSC divisions

2

Maximum number of NSC divisions

5

-

Renewal probability of NSC

0.57

-

Expected number of NSC divisions

3.57

3

Expected NSC G ₁-phase duration

28hr

-

Expected NSC S-phase duration

11hr

8hr

Expected NSC G ₂ M-phase duration

3hr

2hr

Expected NSC duration

42hr

28hr, 28hr

and 52hr⁴