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Table 1 Capabilities of multi-lineage hematopoiesis model

From: An Integrative multi-lineage model of variation in leukopoiesis and acute myelogenous leukemia

Healthy dynamical acceptability criteria
1. Peripheral blood recovers > 80 cells/ μL [58]
2. Stem cells recover > 1 cell/ μL [58]
3. Final dynamic values are within acceptable ranges (Additional file 1: Supplement 4) [40, 59]
4. Marginal pool is within one order of magnitude of peripheral blood [43]
5. Cell counts reduce with chemotherapy to < 20% of original value [63]
6. Recovery overshoot < 12 times value five days after overshoot [hematopoietic stem cell transplant patient data from Dr. Robert Nelson, shown in Additional file 1: Supplement 5].
7. Amplitude of the second peak of oscillations deviates < 18% from the amplitude of the first peak [cutoff calculated, explained in Additional file 5: Supplement 5].