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Table 2 Cancer parameter bounds

From: An Integrative multi-lineage model of variation in leukopoiesis and acute myelogenous leukemia

Parameter Lower bound Upper bound
d Mc 0.0001d M d M
a M c2 0.01a M2 1
m r M c2 0.5m r M2 30
m b Mc 0.0001m b M m b M
  1. Four parameters were varied for determining the most correlated cancer parameter to survival time: the death rate of cancer (d Mc ), the self-renewal probability of cancer progenitor cells (a M c2), the mitosis rate of cancer progenitor cells (m r M c2), and the mobilization rate of cancer stem cells (m b Mc ). The bounds of these parameters were restricted based on the corresponding parameters of monocytes