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Fig. 4 | BMC Systems Biology

Fig. 4

From: A novel interaction perturbation analysis reveals a comprehensive regulatory principle underlying various biochemical oscillators

Fig. 4

Mathematically controlled comparisons among the simple NFO, the activator-amplified NFO variant, the inhibitor-amplified NFO variant, and the type 1 incoherently-amplified NFO variant. Schematic representations and frequency-amplitude plots for the four oscillator models are presented for comparison. In these plots, the changes in the frequency and amplitude due to the perturbations are expressed as a ratio to the frequency and amplitude before the perturbations

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