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Fig. 1 | BMC Systems Biology

Fig. 1

From: Genetic toggle switch controlled by bacterial growth rate

Fig. 1

Schematic of the genetic toggle switch in a growing cell. Schematic shows a replicating bacterial chromosome with the toggle genes inserted in the vicinity of ori (G ori ) and in the vicinity of ter (G ter ). For simplicity, for both genes only one inserted copy is shown. As the chromosome is shown during the replication process, G ori is already replicated while G ter is not yet replicated. Processes of transcription, gene repression and activation occur with the same rates for both genes. To illustrate gene repression and activation processes the two copies of G ori are shown in different states. The ‘upper’ copy is in a repressed state with a dimer D ter bound to the promoter. G ter and the ‘lower’ copy of G ori are in an active state

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