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Table 4 Summaries of the direction of observed trends of the four measurable chemicals, relative to wild type for the four types of experiment: pls mutant, feeding auxin, ethylene and cytokinin respectively (first four columns)

From: Bayesian uncertainty analysis for complex systems biology models: emulation, global parameter searches and evaluation of gene functions

 

Trend relative to wild type with no feeding

Trend relative to pls mutant with no feeding

 

(k 6=0.3, IAA=ACC=cytokinin=0)

(k 6=0, IAA=ACC=cytokinin=0)

Chemical output

pls mutant

Feed Auxin

Feed Ethylene

Feed Cytokinin

pls mutant + Feed Ethylene

 

(k 6=0)

(IAA=1)

(ACC=1)

(cytokinin=1)

(k 6=0 and ACC=1)

Auxin

Down

Up

Up

Down

Down

PLSm

-

Up

Down

Down

-

ET

No change

Up

Up

Up

-

CK

Up

Down

Down

Up

-

  1. The final column gives the trend for the case of feeding ethylene to the pls mutant, relative to the pls mutant with no feeding. See the text and also [30] for more detail on the size and related uncertainties for each of the measured trends