Fig. 7
From: Inferring gene regulatory networks from single-cell data: a mechanistic approach
Fitting marginal distributions from real single-cell data: example of the LDHA gene. The red curve is the stationary distribution associated with our interaction form (here a single gene with auto-activation), while the dashed blue curve corresponds to the basic two-state model in the bursty regime (Gamma distribution). a The raw data seems to be well fitted by the Gamma distribution, which in this view is close to our model. b Same fit viewed after applying the transformation x↦x 1/3. The data becomes bimodal and the fit appears to be better with the auto-activation model