Fig. 3From: Metabolic adaptation of two in silico mutants of Mycobacterium tuberculosis during infectionFlux distributions at key enzymes in the pfkA-mutant during shifts in glucose and oxygen concentration. Negative and positive fluxes represent backward and forward sense of the reaction. pgi: glucose-6-phosphate isomerase, serA: phosphoglycerate dehydrogenase, pckA: PEP carboxykinase, icd1/2: isocitrate dehydrogenase, frdA~D: fumarate reductase, mdh: malate dehydrogenase, fumC: fumarase, acn: aconitase, mutAB: methylmalonyl-CoA mutase, accA3: acetyl-CoA carboxylase, fgd1: glucose-6-phosphate dehydrogenase, pykA: pyruvate kinaseBack to article page