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Table 2 The compound targets were proved in the previous literatures

From: A linear programming computational framework integrates phosphor-proteomics and prior knowledge to predict drug efficacy

NO. Compound treatment Up-regulation Down-regulation PMID
1 Fulvestrant   ER 26,272,024
2 Paclitaxel JNK BCL2 22,433,870
3 Staurosporine   PKC 17,171,646
4 Irinotecan HIF1, NFKB ER 24,966,994
5 Scriptaid   HDAC1 14,620,913
6 Anisomycin   BCL2 23,261,849
7 Trichostatin   HDAC1 24,626,188
8 MS-275   HDAC1 18,579,665
9 Digoxin   HIF1 19,020,076
10 Geldanamycin   HSP90 26,674,599, 26,405,178