A linear programming computational framework integrates phosphor-proteomics and prior knowledge to predict drug efficacy

Table 2 The compound targets were proved in the previous literatures

NO.	Compound treatment	Up-regulation	Down-regulation	PMID
1	Fulvestrant		ER	26,272,024
2	Paclitaxel	JNK	BCL2	22,433,870
3	Staurosporine		PKC	17,171,646
4	Irinotecan	HIF1, NFKB	ER	24,966,994
5	Scriptaid		HDAC1	14,620,913
6	Anisomycin		BCL2	23,261,849
7	Trichostatin		HDAC1	24,626,188
8	MS-275		HDAC1	18,579,665
9	Digoxin		HIF1	19,020,076
10	Geldanamycin		HSP90	26,674,599, 26,405,178

ISSN: 1752-0509