Fig. 8

The stability of the models against variation in regression parameters. The regression parameter ranges of linear (a), quadratic (b), and cubic polynomial models (c), as well as the quadratic polynomial model with correlated gene pairs (d). Overall, 32 genes are adopted from the apoptosis pathway, and 6 pairs of them have relationships of transcription regulation. Thus, there are 33, 65, 97 and 71 parameters in the regression functions of linear, quadratic, cubic polynomial models, and the quadratic polynomial model with correlated gene pairs, respectively