Fig. 4

Topological distributions of High-MI/High-RD edges and their incident nodes in T-LGL signaling network. a-b Distributions of High-MI and High-RD edges, respectively, and their incident nodes. c-d Subgraphs with respect to High-MI-incident and High-RD-incident nodes, respectively. Red link and yellow node represent High-MI edge and High-MI-incident node, respectively, in both (a) and (c), whereas they represent High-RD edge and High-RD-incident node, respectively, in both (b) and (d). (see Additional file 1: Fig. S16-S17 for the results of STF and HIV-1 networks.)