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Table 4 Comparison of independent testing results among various models in this work

From: MDD-carb: a combinatorial model for the identification of protein carbonylation sites with substrate motifs

Residue Model Sn Sp Acc MCC AUC
K Single SVM trained with AAC 0.65 0.68 0.67 0.31 0.72
Single SVM trained with PWM 0.67 0.68 0.68 0.33 0.73
Single profile HMM trained from all data 0.69 0.68 0.69 0.35 0.74
Multiple profile HMMs trained from MDDLogo-clustered subgroups 0.85 0.47 0.60 0.31 0.68
Single SVM trained from multiple profile HMMs (MDD-Carb) 0.80 0.76 0.77 0.53 0.84
R Single SVM trained with AAC 0.62 0.62 0.62 0.23 0.66
Single SVM trained with PWM 0.65 0.65 0.65 0.29 0.70
Single profile HMM trained from all data 0.68 0.66 0.67 0.33 0.72
Multiple profile HMMs trained from MDDLogo-clustered subgroups 0.90 0.55 0.67 0.44 0.81
Single SVM trained from multiple profile HMMs (MDD-Carb) 0.79 0.73 0.75 0.49 0.83
T Single SVM trained with AAC 0.63 0.71 0.69 0.34 0.73
Single SVM trained with PWM 0.67 0.71 0.70 0.36 0.74
Single profile HMM trained from all data 0.67 0.71 0.70 0.36 0.74
Multiple profile HMMs trained from MDDLogo-clustered subgroups 0.93 0.56 0.69 0.48 0.80
Single SVM trained from multiple profile HMMs (MDD-Carb) 0.79 0.76 0.77 0.53 0.84
P Single SVM trained with AAC 0.63 0.61 0.62 0.23 0.66
Single SVM trained with PWM 0.69 0.67 0.68 0.34 0.74
Single profile HMM trained from all data 0.69 0.67 0.68 0.34 0.74
Multiple profile HMMs trained from MDDLogo-clustered subgroups 0.88 0.49 0.62 0.35 0.76
Single SVM trained from multiple profile HMMs (MDD-Carb) 0.77 0.74 0.75 0.49 0.82