Fig. 5

a Duration of Action as a function of nuclease-induced degradation rate (λ _s ) with different unbinding rates (k _soff =0.02,0.2,1 min⁻¹), under no molecular stripping (k _s =0 μM⁻¹min⁻¹) and with molecular stripping (k _s =10 μM⁻¹min⁻¹).Dose of NFκB synthetic decoy ODNs is set to be 1 μM. b Duration of Action as a function of dose of NFκB synthetic decoy ODNs under different degradation rates (λ _s =0.001,0.005,0.02 min⁻¹), under slow unbinding rate (k _soff =0.02 min⁻¹) and fast unbinding rate (k _soff =1 min⁻¹), under no molecular stripping (k _s =0 μM⁻¹min⁻¹) and with molecular stripping (k _s =10 μM⁻¹min⁻¹)