Table 15 List of model equations used in calculation of ER Ca2+ handling (modified from [21])
Equation | Biological significance |
|---|---|
Jer,out=(VIP3∗((IP3/(IP3+dIP3))3)∗((CAC/(CAC+d ACT ))3)∗(h3)+v leak )∗(CAER−CAC) | IP3 receptor and leak |
\( J_{serca} = V_{serca} * CAC^{2}/\left (k_{serca}^{2}+CAC^{2}\right) \) | SERCA pump |