Table 5 List of initial conditions [7–9]
Parameters | Value | Biological significance |
|---|---|---|
PSI(0) | 164 mV | Base potential at time 0 |
CAM(0) | 0.05 μM | Mitochondrial Ca2+ concentration at time 0 |
CAC(0) | 0.05 μM | Cytosolic Ca2+ concentration at time 0 |
CAER(0) | 11 μM | ER Ca2+ concentration at time 0 |
ADP m (0) | 4.46 mM | Mitochondrial ADP concentration at time 0 |
ADP i (0) | 0.028 mM | Cytosolic ADP concentration at time 0 |
NADH m (0) | 0.16 mM | Mitochondrial NADH concentration at time 0 |
h(0) | 95% | Percentage of closed channels at time 0 |
a(0) | 0 mM | β-amyloid concentration at time 0 |
y(0) | 0 | Secondary slow process involved in PTP opening at time 0 |
PTP h (0) | 0 | PTP closed at time 0 |
PTP l (0) | 0 | PTP closed at time 0 |