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Table 1 Simulation settings

From: GxGrare: gene-gene interaction analysis method for rare variants from high-throughput sequencing data

Index Simulation settings
Weight Effect model Conditions
1 No weight Only interaction effect Unidirectional
2 No weight Interaction + marginal effect Unidirectional
3 No weight Only interaction effect Bidirectional
4 MAF weight Only interaction effect Unidirectional
5 CONS weight (0.5) Only interaction effect Unidirectional
6 CONS weight (0.8) Only interaction effect Unidirectional
7 CONS weight (1.0) Only interaction effect Unidirectional
8 CONS weight (0.5) Interaction + marginal effect Unidirectional
9 CONS weight (0.75) Interaction + marginal effect Unidirectional
10 CONS weight (1.0) Interaction + marginal effect Unidirectional