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Table 2 Correlation coefficients of 31 cell lines calculated by the Extremely Randomized Trees model

From: In silico drug combination discovery for personalized cancer therapy

Cell line name Site Correlation coefficient Best observed Its predicted rank out of
    drug combination N drug combinations
RPMI7951 Skin 0.893 MK-4827.TEMOZOLOMIDE 1 out of 88
HCT116 Colon 0.892 ETOPOSIDE.MK-2206 7 out of 105
HT29 Colon 0.889 AZD1775.MK-8776 2 out of 116
SW620 Colon 0.874 BEZ-235.MK-8669 1 out of 108
PA1 Ovarian 0.868 MK-2206.SUNITINIB 5 out of 85
A2780 Ovarian 0.865 DASATINIB.MK-5108 1 out of 112
MDAMB436 Breast 0.864 MK-4827.TEMOZOLOMIDE 1 out of 114
VCAP Prostate 0.856 BEZ-235.MK-8669 1 out of 109
LOVO Colon 0.839 MK-4827.TEMOZOLOMIDE 1 out of 121
OV90 Ovarian 0.833 AZD1775.MK-8776 1 out of 99
OCUBM Breast 0.831 AZD1775.MK-8776 1 out of 62
NCIH1650 Lung 0.83 DASATINIB.MK-2206 2 out of 91
A2058 Skin 0.829 MK-4827.MK-8776 28 out of 119
SKMES1 Lung 0.825 BEZ-235.MK-8669 1 out of 113
A427 Lung 0.807 MK-8776.TEMOZOLOMIDE 9 out of 105
SKOV3 Ovarian 0.798 ERLOTINIB.MK-8669 3 out of 105
UACC62 Skin 0.797 GEMCITABINE.MK-8776 5 out of 120
DLD1 Colon 0.79 MK-2206.MK-8669 2 out of 116
ES2 Ovarian 0.789 BEZ-235.MK-8669 1 out of 125
NCIH2122 Lung 0.766 DEXAMETHASONE.MK-2206 8 out of 137
SKMEL30 Skin 0.709 BEZ-235.MK-8669 1 out of 105
A375 Skin 0.691 MK-4827.TEMOZOLOMIDE 1 out of 103
RKO Colon 0.688 GELDANAMYCIN.PD325901 20 out of 117
HT144 Skin 0.669 MK-2206.SN-38 7 out of 124
NCIH520 Lung 0.643 DASATINIB.TOPOTECAN 20 out of 124
UWB1289 Ovarian 0.63 BEZ-235.MK-8669 1 out of 125
MSTO Lung 0.628 BEZ-235.MK-8669 1 out of 86
SW837 Colon 0.626 BEZ-235.DASATINIB 8 out of 110
OVCAR3 Ovarian 0.554 AZD1775.SN-38 5 out of 93
T47D Breast 0.493 DOXORUBICIN.MK-8669 1 out of 61
NCIH23 Lung 0.478 L778123.MK-8669 2 out of 117