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Fig. 8 | BMC Systems Biology

Fig. 8

From: Constraints on signaling network logic reveal functional subgraphs on Multiple Myeloma OMIC data

Fig. 8

Overview of the application case. a: Subgraph obtained from the PID-NCI database, 2269 nodes and 2683 edges. CD40, IL6 and IGF1 are the 3 queried pathways connecting 529 differentially expressed genes. b: Components and their interactions. Simple components are labeled with the Uniprot identifiers of genes. The two most significant and larger components are colored in red. c: Graph representing the component 2, 422 nodes (167 genes) and 450 edges. Labeled nodes refer to Uniprot identifiers of genes. Unlabeled nodes refer to other biological compounds: proteins, complexes, transcription or proteins modification events

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